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MRCOG PART 2 SBAs and EMQs

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notes336
EMQ1502
SBA2115
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Pattern of inheritance and statistics

Pattern of inheritance and statistics Posted by Sameera C.
Dear Paul,
Please guide me regarding the MCQs based on the diagram of the family tree and pattern of inheritance. Some help is necessary regarding the MCQs on statistics also. Could u please see the past papers of MCQs from RCOG. There are few questions which are given repeatedly but they don\'t appear in your MCQ tests. We are trying to search for the answers but not sure about the answers.
badly in need of your help regarding the past papers.
Sameera
Posted by Sameera C.
(M)---I------F
I
l-----------------------------------------------------------------------
l l l l
------- M -------F M F-----------(M)
l l l l
F M ----------------- -----------------
l l l l l l l
M F F M F (F) (F)

M=normal male (M) affected male F= normal female (F)=affected female
The following conditions would be expected to conform to the pattern of inheritance shown in the above figure

achondroplasia
phenylketonuria
neurofibromatosis
cystic fibrosis
myotonic dystrophy
Dear Paul
please give guidance regarding this type of questions to identify AD,AR, X linked recessive patterns of inheritance on seeing the flow chart or suggest a book to read about this topic
Sameera
Posted by Sameera C.
Dear Paul,
I couldn\'t paste the diagram properly. If u don\'t mind the question is from Past papers March 1997 Question No 116-120.
Sameera
Posted by Sarwat F.
i have solved it as follows
116 true
117 false
118 true
119 false
120 true
the figure shows pattern of inheritance of autosomal dominant conditions. note 50 % inheritance
Posted by Sameera C.
Thank u very much
Sameera