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MRCOG PART 2 SBAs and EMQs

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EMQ1470
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part 2 mcq

part 2 mcq Posted by ELIZA SHIREEN E.
woman who develop breast cancer while taking combined HRT have bigger tumour and more advance disease.Why is it not associated with worse prognosis?In MCQ it is false.Why?
Tamoxifen use associated with increase risk of VTE 4.7-5.7 fold. It should not be discontinued before major surgery.
Raloxifene use associated with increase risk of VTE 3.1.But it should be discontinued before major surgery.Why?
Posted by PAUL A.
woman who develop breast cancer while taking combined HRT have bigger tumour and more advance disease.Why is it not associated with worse prognosis?In MCQ it is false.Why? That is the evidence from RCTs - more advanced tumours does not necessarily mean significant increase in mortality. Mortality from stage Ia tumours is not necessarily greater than for stage Ib tumours

Tamoxifen use associated with increase risk of VTE 4.7-5.7 fold. It should not be discontinued before major surgery.
Raloxifene use associated with increase risk of VTE 3.1.But it should be discontinued before major surgery.Why?

Probably related to primary indication for treatment: tamoxifen - breast cancer; raloxifene - osteoporosis. If you had breast cancer and were on tamoxifen, would you stop treatment?