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MRCOG PART 2 SBAs and EMQs

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SBA 7

SBA 7 Posted by PAUL A.

Question1

During development, the gonads acquire male / female characteristics

a)    By 6 weeks gestation

b)    During the 7th week of development                    

c)    By 12 weeks gestation

d)    During the 16th week of development

e)    By 16 weeks gestation

 

Question2

 

With respect to sexual development in-utero

 

a)    In the absence of a Y chromosome, a male phenotype can still develop

 

b)    In the absence of a gonad, a male phenotype can still develop

 

c)    Normal ovarian development can occur in the presence of only one X chromosome

 

d)    A male phenotype would develop if a Y chromosome is present

 

In the absence of a gonad, a female phenotype would develop

 

Question3

 

During sexual development in-utero

 

a)    Germ cells appear in the gonadal ridges in the 6th week of development              

 

b)    Germ cells develop in the primitive streak

 

c)    Gonadal ridges develop from the epithelium of the cloaca

 

d)    Germ cells appear in the gonadal ridges in the 12th week of development

 

e)    Germ cells migrate from the gonadal ridges to the yolk sac during the 6th week of development

 

Question4

Mullerian inhibiting factor is produced by

a)    Leydig sells

b)    Sertoli cells               

c)    Coelomic epithelial cells

d)    Oogonia

e)    Ovarian stromal cells

 

Question5

 

During sexual development in-utero

 

a)    Testosterone is produced by Leydig cells from 12th week

 

b)    Testosterone is produced by Sertoli cells from 12th week of development

 

c)    Testosterone is produced by Leydig cells from 6th week of development

 

d)    Testosterone is produced by Leydig cells from 8th week of development               

 

e)    Testosterone is produced by Sertoli and Leydig cells from 12th week of development

 

Question7

 

During in-utero sexual development, the Mullerian duct is sensitive to Mullerian inhibiting factor

 

a)    From the 8th week of development

 

b)    Up to the 8th week of development                       

 

c)    From the 12th week of development

 

d)    Up to the 12th week of development

 

e)    Before the 16th week of development

 

Question8

 

During in-utero development, testosterone influences the development of

 

a)    The gonadal ridges and the Mullerian duct

 

b)    The Mullerian ducts and the Wolffian ducts

 

c)    The external genitalia and the Mullerian ducts

 

d)    The external genitalia and the Wolffian ducts                

 

e)    The gonadal ridges and the external genitalia

 

Question9

 

During in-utero development

 

a)    The Mullerian ducts degenerate in the female

 

b)    The mesonephric ducts degenerate in the male

 

c)    The development of the mesonephric ducts is under the direct influence of testosterone

 

d)    The cranial portion of the Wolffian ducts form the fallopian tubes in the female

 

e)    The fused Mullerian ducts form the uterus in the female                    

 

Question10

 

With respect to the development of the genital tract, the cervix is formed from

 

a)    The fused Mullerian ducts             

 

b)    The cloaca

 

c)    The urogenital sinus

 

d)    The mesonephros

 

e)    The fused Wolffian ducts 

Posted by koukab abdullah A.

1-B

2-E

3-E

4-A

5-D

6-B

7-D

8-E

9-E

 

Posted by PAUL A.

Answers

 

1)   B

2)   E

3)   A

4)   B

5)   D

6)   B

7)   D

8)   E

9)   A

querries Posted by Anuradha M.

Pls explain Q-8. As per EBM, testosterone influences development of wolffian duct and male externa  genitalia

Testosterone acts through the androgen receptor and causes development of the Wolffian ducts into the vasa deferentia, and later the seminal vesicles and epididymides

querry Posted by Anuradha M.

ALso same thing in Q-9 option C, why is option c not correct? As the mesonephric duct is same as the wolffian duct and its development occurs under the influence of testosterone.

ANswer Posted by Anuradha M.

Q-10 is answer a?