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Tamoxifen

Tamoxifen Posted by ghada S.

QDear Paul : could you please explain this as regard TAMOXIFEN &HRT

1)How does tamoxifen increase serum estradiol despite level of gonadotrophin as unchanged??

2)Why doesn't  Tamoxifen  improve hot flushes despite it increases seum estradiol??

3)When to give combined continuous HRT& when to give sequential HRT??

 Thank you very much