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MRCOG PART 2 SBAs and EMQs

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EMQ1476
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Intraperitoneal chemotherapy for ovarian carcinoma

Intraperitoneal chemotherapy for ovarian carcinoma Posted by Dhivya C.

Dear Dr.Paul

Busyspr notes:

Treatment options for patients with optimally cytoreduced stage III disease:

  • Intra-peritoneal chemotherapy

Using cisplatin or paclitaxel is associated with longer progression-free survival and overall survival compared to intravenous chemotherapy.
Toxic effects are greater in women receiving intra-peritoneal chemotherapy
The rate of completion of six cycles of treatment is also less frequent in women receiving intra-peritoneal chemotherapy because of the toxic effects and catheter-related problems

NICE guidelines 2011

Intraperitoneal chemotherapy

Do not offer intraperitoneal chemotherapy to women with ovarian cancer, except as part of a clinical trial.

Can we use intraperitoneal chemotherapy for ovarian carcinoma. Could you please clarify this also.

Many thanks

Dhivya